Physician Scientist Oncology Training Program

描述（由申请人提供）：UT西南医师科学家肿瘤学培训计划将为完成肿瘤学临床培训的研究员和住院医师提供机会和保护时间，以发展成功的实验室肿瘤研究项目的技术和智力技能。该计划将通过提供高度个性化的指导，在我们国际知名教师的研究实验室进行培训的机会以及在研究培训期间长达三年的津贴支持来实现这一目标。具体来说，该计划的目标是通过提供(a)研究癌症发病机制和生物学所需的实验室技能培训，(b)在癌症生物学、生物统计学、伦理学和监管问题方面提供严格的指导和教学计划，支持完成肿瘤亚专业临床培训的医生，并培训他们进行基于实验室的肿瘤转化研究。(c)在研究与临床相关的基本癌症问题以及将临床观察转化为基于假设的实验室问题方面进行培训。受训者将主要由参与癌症中心五个项目之一的科学家指导，但也将有次要的临床研究资源教师导师，以确保受训者发展临床技能和必要的专业知识，以成功地采用多学科方法研究临床相关的癌症问题。该项目的独特机会包括生物科学研究生院癌症生物学培训项目的优秀教师，肺癌卓越研究专业项目，以及与人类癌症相关的细胞内通路的协同化学，生物物理和分子生物学攻击项目项目资助，来自15个不同部门和中心的20名实验室导师致力于该项目。还有11位临床资源导师。由癌症中心的7位资深医生和科学家领导组成的指导委员会将提供监督和指导，癌症中心将提供行政支持。

DESCRIPTION (provided by applicant): The UT Southwestern Physician Scientist Oncology Training Program will provide fellows and residents who have finished their clinical training in oncology the opportunity and protected time to develop the technical and Intellectual skills for a successful laboratory based oncology research program. The program will accomplish this by providing highly Individualized mentorship, the opportunity to train in the research laboratories of one of our internationally renowned faculty and up to three years of stipend support during the years of their research training. Specifically, the goals of the program are to support physicians who have finished their subspecialty clinical training in oncology and train them in lab-based translational oncology research, by providing (a) training in the laboratory skills necessary to investigate the pathogenesis and biology of cancer, (b) a rigorous mentoring and didactic program in the biology of cancer, biostatistics, ethics, and regulatory issues, (c) and training in the investigation of basic cancer questions which are clinically relevant, and in the translation of clinical observations into hypothesis based laboratory questions. Trainees will be mentored primarily by scientists who participate in one of the five programs in the Cancer Center, but will also have secondary, clinical research resource faculty mentors to ensure that the trainee develops the clinical skills and expertise necessary to succeed in a multi-disciplinary approach to the study of clinically relevant cancer questions. Unique opportunities of the program include the outstanding faculty of Cancer Biology Training Program for pre-and post doctoral PhDs within the Graduate School of Biological Sciences, a Specialized Program of Research Excellence in Lung Cancer, and a Program Project Grant on the Concerted Chemical, Biophysical and Molecular Biological Attack of Intracellular Pathways Relevant to Human Cancer. 20 laboratory mentors representing 15 different Departments and Centers are committed to this program, as are 11 clinical resource mentors. A Steering Committee consisting of 7 senior physician and scientist leaders in the Cancer Center will provide oversight and direction, and administrative support will be provided by the Cancer Center. RELEVANCE: The goal of this program is to produce top-quality physician scientists who are committed to an academic career in patient-related basic and/or translational oncology research.