Radiation biology training grant

描述（由申请人提供）：这是一个旨在培训辐射生物学家的计划的培训补助金提案的竞争性更新，辐射生物学家将了解辐射的分子，细胞和组织效应。6名博士后和4名博士后研究生。将在宾夕法尼亚大学医学院肿瘤学研究部的放射生物学和相关实验室提供培训。该计划将涉及正式的课程，系列讲座和期刊俱乐部，旨在满足我们的培训需求，研究研讨会和会议以及实验室研究项目，由既定的调查人员监督。研究项目将侧重于参与实验室目前资助的研究领域的各个方面;对于研究项目，学员将利用现代生物学开发的技术进行放射生物学/肿瘤学的机械导向研究。14名培训导师所从事的研究领域广泛，涉及癌症研究，包括致癌和诱变的分子机制、分子和细胞辐射生物学、辐射化学和生物化学、DNA修复过程、癌症预防和辐射肿瘤学。预计培训计划的毕业生将继续从事放射生物学和肿瘤学的研究和学术事业。

DESCRIPTION (provided by applicant): This is a competitive renewal of a training grant proposal for a program designed to train radiation biologists who will have knowledge of the molecular, cellular and tissue effects of radiation. 6 predoctoral and 4 postdoctoral trainees are requested. Training will be offered in the radiation biology and associated laboratories of the Division of Oncology Research at the University of Pennsylvania School of Medicine. The program will involve formal coursework, a lecture series and a journal club designed for our training needs, research seminars and conferences and laboratory research projects to be supervised by established investigators. The research projects will focus on various aspects of the currently funded research areas in the participating laboratories; for research projects, trainees will utilize techniques developed in modern biology to perform mechanistically-oriented studies in radiation biology/oncology. The research areas in which the 14 training preceptors are involved are broadly based in cancer research, including molecular mechanisms of carcinogenesis and mutagenesis, molecular and cellular radiation biology, radiation chemistry and biochemistry, DNA repair processes, cancer prevention and radiation oncology. It is expected that graduates of the training program will continue with their research and academic careers in radiation biology and oncology.