ENDOSCOPIC ASSESSMENT OF SWALLOWING IN HEALTHY ADULTS - GCRC PILOT STUDY

这个子项目是许多研究子项目中利用 资源由NIH/NCRR资助的中心拨款提供。子项目和 调查员(PI)可能从NIH的另一个来源获得了主要资金， 并因此可以在其他清晰的条目中表示。列出的机构是 该中心不一定是调查人员的机构。 20年来，它已成为60多份同行评议出版物的重要评价工具。然而，令人惊讶的是，通过内窥镜评估，关于正常吞咽的数据很少。我们的长期目标是获得经内窥镜评估的有关吞咽的广泛的标准化数据，并获得关于我们所选择的内窥镜吞咽措施的评价者间和评价者内可靠性的全面数据。我们的长期目标是获得经内窥镜评估的有关吞咽的广泛的标准化数据，并获得关于我们所选择的内窥镜吞咽措施的评价者间和评价者内可靠性的全面数据。然而，对于R03拨款申请，有两个特定的目标将获得初步/试点数据，以实现我们的长期目标。 具体目的这笔赠款中的一项需要四个单独的实验来确定七个不同因素/问题对内窥镜吞咽测量的影响。 具体目标二将确定在20%的分层数据中选择的四种吞咽内窥镜测量在评价者之间和评价者内部的可靠性，以代表不同的年龄和团注类型。评分员内部的可靠性将作为短期和长期重复评级的函数进行评估。评分员之间的可靠性将根据9名独立评分员的三个级别的临床医生费用经验(即初级、中级和高级)进行评估，而不需要进行预培训。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. 20 years and it has been the swallowing evaluation tool in over 60 peer-reviewed publications. However, amazingly scant data exists on normal swallowing as assessed endoscopically. Our long-range objectives are to obtain extensive normative data on swallowing as assessed endoscopically and to obtain comprehensive data on the inter- and intra-rater reliability of the endoscopic swallowing measures we have chosen. Our long-range objectives are to obtain extensive normative data on swallowing as assessed endoscopically and to obtain comprehensive data on the inter- and intra-rater reliability of the endoscopic swallowing measures we have chosen. However, for this R03 grant application, there are two specific aims that will obtain preliminary/pilot data towards our long-range objectives. Specific Aim One of this grant requires four separate experiments to determine the effects of seven different factors/issues on endoscopic swallowing measurements. Specific Aim Two will determine the inter- and intra-rater reliability of the four endoscopic measurements of swallowing chosen on 20% of the data stratified to represent various ages and bolus types. Intra-rater reliability will be assessed as a function of short- and long-term repeat ratings. Inter-rater reliability will be assessed as a function of three levels of clinician FEES experience (i.e., beginning, intermediate, and advanced) across nine independent raters without pre-training.