Mount Sinai Injury Control Research Center

描述(由申请人提供)：这份支持西奈山伤害控制研究中心(MS-ICRC)的提案由纽约市西奈山医学院(MSSM)提交。 康复医学部在这方面发挥了带头作用，吸收了MSSM其他学科(急诊医学、社区医学)以及第二地区其他机构的相关专门知识和参与，这些机构包括哥伦比亚大学内科和外科医学院、新泽西医学和牙科大学肯尼迪康复研究所和国家康复医院。MS-ICRC的主要主题是提高经历过创伤性脑损伤的个人的生活质量(QOL)。 将沿着三条道路进行研究：1)制定更好的康复干预措施，以改善脑外伤患者的预后；2)制定办法，更好地识别有长期残疾风险的轻度脑损伤患者；3)制定一种方法，以确定脑损伤患者的长期需求，以此为基础记录伤残情况，并确定旨在二级预防的二级伤害控制议程要素的优先次序。 将提出五个项目，两个大的和三个小的：1)将实施一项RCT，以记录持续有氧运动对脑外伤患者认知功能和情绪的影响，这些患者既有轻度的，也有中到重度的；2)第二项RCT将评估一项综合的日间计划的影响，该计划侧重于改善参与者的执行功能和注意力，对他们在社区的功能和感知的生活质量产生长期影响；3)一个人在三个急诊室出现轻微脑损伤后出现的症状将在六个月内得到跟踪，同时评估教育那些在经历了精神状态改变的头部WOW后从急诊室出院的人有关脑损伤的不同教育方法的对比方法；4)脑损伤筛查问卷将通过证明其在识别脑损伤后症状的敏感和具体模式方面的效用而得到验证，这种模式与其他慢性病患者的模式不同；5)将对I-CAN进行评估，这是一种识别脑外伤患者感知需求的新方法：为记录一段时间内的服务需求提供基础，并向疾病预防控制中心等机构提供系统的投入，表明它们在被要求时将建立的“研究议程”。 此外，MS-ICRC还纳入了针对专业人员和消费者的综合培训方案以及知识翻译。正在计划一项培训博士前研究人员的方案，以及努力在西奈山医学院内制定课程，以解决伤害控制/预防目标。计划建立一个网站、为新发现的创伤性脑损伤患者编写培训材料、其他面向消费者的培训以及面向专业人员的传播，所有这些都是实现三级预防和预防继发性残疾的手段。最后，将提供资金支持SEED项目，以加强区域II内研究人员的伤害控制结构。因此，MS-ICRC的成果将通过广泛的知识转化活动传播，特别是在拟建中心的第3-5年。

DESCRIPTION (provided by applicant): This proposal to support the Mount Sinai Injury Control Research Center (MS-ICRC) is submitted by the Mount Sinai School of Medicine (MSSM), New York City. The lead in this effort has been taken by the Department of Rehabilitation Medicine, drawing in relevant expertise from and participation of other disciplines within MSSM (emergency medicine, community medicine), as well as from other institutions in Region II: Columbia University College of Physicians and Surgeons, JFK Rehabilitation Institute of the University of Medicine and Dentistry of New Jersey and The National Rehabilitation Hospital. The major theme of the MS-ICRC is enhancing quality of life (QOL) of individuals who have experienced traumatic brain injury (TBI). Research will be pursued along three paths: 1) developing better rehabilitation interventions aimed at improve outcomes for individuals with TBI, 2) developing approaches to better identify those individuals with mild TBI who are at risk of long-term disability, and 3) developing a method to identify the long-term needs of individuals with TBI as the basis for documenting disablement and for prioritizing the elements of a secondary injury control agenda aimed at secondary prevention. Five projects, two large and three small, are being proposed: 1) An RCT will be implemented to document the impact of sustained aerobic exercise on the cognitive functioning and mood of individuals with TBI, both those with "mild" as well as moderate to severe injuries; 2) A second RCT will evaluate the impact of a comprehensive day program focused on improving executive functions and attention of participants, with long-term impact on their functioning in the community and on perceived quality of life; 3) Patterns of symptoms that emerge after an individual presents with mild TBI within three emergency departments will be tracked over six months, while at the same time evaluating contrasting approaches for educating people about TBI who are discharged home from the ED after experiencing a Wow to the head with altered mental status; 4) The Brain Injury Screening Questionnaire will be validated by demonstrating its utility in identifying sensitive and specific patterns of post-TBI symptomatology that is distinguishable from patterns found in persons with other chronic conditions; and 5) The I-CAN, a new method for identifying perceived needs of individuals with TBI, will be evaluated: to provide the basis for documenting service needs over time and for providing systematic input to agencies, such as CDC, indicating the "research agenda" they would established when asked. In addition, a comprehensive program of training for both professionals and consumers and knowledge translation is incorporated as part of the MS-ICRC. A program for training pre-doctoral researchers is planned, as are efforts to shape curricula within the Mount Sinai School of Medicine to address injury control / prevention objectives. A website, training materials for newly identified individuals with TBI, other consumer-oriented training, as well as professionally-oriented dissemination are all planned as means of effecting tertiary prevention and prevention of secondary disability. Finally, funds will be made available to support seed projects, as a means of bolstering the injury control structure of researchers within Region II. Thus, the results emerging from the, MS- ICRC will be disseminated through extensive knowledge translation activities, particularly in Years 3-5 of the proposed Center.