Modeliing immunity for Biodefense:Enteroagressive E. coli and Helicobacter pylori

生物防御免疫建模计划支持创建新的或改进的数学模型的研究，这些模型能够从标准或复杂的数据集生成知识，并指导进一步的实验，以推进免疫学或基于免疫的疗法的研究。该计划还支持配套的免疫学实验，以提供模型开发和测试所需的数据。具体而言，活动范围包括： ？通过综合和分析复杂和/或标准数据集，开发和改进用于知识发现的数学和计算模型。 ？通过迭代过程评估模型功能，需要获取定量免疫测量来开发、测试、验证和改进计算模型。 ？建立生物信息学部门，以维持免疫数据数据库并开发免疫建模工具。 ？为更广泛的研究界开发一个由暑期学校计划和座谈会组成的教育部分，以促进在研究对感染或基于免疫的疗法的免疫反应时使用数学和计算模型。

The Modeling Immunity for Biodefense Program supports research to create new or improved mathematical models that are able to generate knowledge from standard or complex datasets and guide further experimentation to advance the study of immunology or immune-based therapies. The program also supports accompanying immunological experimentation to provide the data required for model development and testing. Specifically, the scope of activities includes: ¿ Development and refinement of mathematical and computational models to be used for knowledge discovery through integration and analysis of complex and/or standard datasets. ¿ Assessment of model functionality thought the iterative process, requiring the acquisition of quantitative immunological measurement for developing, testing, validating, and refining the computational models. ¿ Establishment of a bioinformatics component to maintain a database of immunological data and develop immune modeling tools. ¿ Development of an educational component consisting of summer school programs and symposia for the broader research community to promote the use of mathematical and computational modeling in studies of immune responses to infection or immune-based therapies.