TAS::75 0893::TAS THIOAPTAMER CAPTURE FOR ADDICTION-RELEVANT PROTEINS

AM生物技术公司(AM)将开发可再生的硫代适配子蛋白质捕获试剂，以捕获与药物成瘾相关的10种蛋白质。硫代适配子是一类含有磷酸二硫酸键和其他修饰的适配子，对蛋白质具有良好的亲和力和特异性。由于硫代适配子的独特化学组成，它们不能用指数配基系统进化(SELEX)扩增方法来开发。

AM Biotechnologies (AM) will develop renewable thioaptamer protein capture reagents to ten proteins related to drug addiction. Thioaptamers are a type of aptamer containing phosphorodithioate linkages and other modifications that have excellent affinity and specificity for proteins. Because of the unique chemical composition of thioaptamers, they cannot be developed using the Systematic Evolution of Ligands by Exponential (SELEX) amplification method.