Clinical Orthopaedic and Musculoskeletal Education and Training Program

描述(由申请人提供)：肌肉骨骼和骨科疾病非常普遍，致残，费用高昂。然而，由于缺乏训练有素的临床和翻译研究人员的强大渠道，对这些情况的研究受到阻碍。COMET(临床整形外科和肌肉骨骼教育和培训)计划于2008年在NIAMS T32的支持下启动，以增加整形外科和肌肉骨骼条件下的临床研究培训机会。COMET计划在第一个周期非常成功，六名项目毕业生中有五名仍在学术岗位上，六名毕业生中有三名获得了K-Level NIH职业发展奖。这项申请建议更新彗星T32计划。我们增加了四个新的教员和四个新的研究单位，以提供更多在妇女健康和骨骼健康方面的临床、肌肉骨骼研究机会。COMET T32培训基金的目标是为博士后和博士后候选人提供涉及肌肉骨骼和骨科疾病的临床、翻译、流行病学和政策研究方面的严格培训计划。该计划侧重于这些疾病的预防、识别、负担和影响，以及手术和非手术治疗。研究领域包括骨关节炎、骨质疏松症、区域性疾病(脊柱、膝盖、肩部、上肢、足踝)、关节和软组织问题、神经卡压、慢性疼痛和相关疾病。该计划支持一系列互补学科的培训，包括流行病学、生物统计学、药物流行病学、决策科学、经济分析、健康差异和行为干预。本申请要求每年提供两个博士后和三个博士后培训职位的资金。实习生在该项目中至少学习两年。那些之前没有接受过正规教学培训的人获得了哈佛大学公共卫生学院临床有效性项目的硕士学位。这些教师包括来自哈佛医学院、哈佛公共卫生学院、布里格姆妇女医院和其他哈佛医疗机构的杰出导师。教职员工在广泛的临床领域和方法学科上进行研究。在最初的资助期，彗星T32计划已经开始满足肌肉骨骼疾病临床研究培训机会的需求。这一续签申请建立在该计划早期成功的基础上，并进一步促进了促进研究以改善肌肉骨骼疾病患者的生活质量的总体计划目标。

DESCRIPTION (provided by applicant): Musculoskeletal and orthopaedic disorders are highly prevalent, disabling and costly. However research on these conditions is hampered by the lack of a robust pipeline of rigorously trained clinical and translational researchers. The COMET (Clinical Orthopedic and Musculoskeletal Education and Training) Program was launched with NIAMS T32 support in 2008 to bolster opportunities for clinical research training in orthopedic and musculoskeletal conditions. The COMET program was highly successful in its first cycle, with five of six program graduates remaining in academic positions and three of six obtaining K-level NIH Career Development Awards. This application proposes a renewal of the COMET T32 program. We have added four new faculty and four new research units to provide increased clinical, musculoskeletal research opportunities in women's health and skeletal health. The objectives of the COMET T32 training grant is to provide pre- and postdoctoral candidates with a rigorous program of training in clinical, translational, epidemiological and policy research involving musculoskeletal and orthopaedic disorders. The program focuses on prevention, recognition, burden and impact of these disorders and operative and nonoperative treatment. The research areas include osteoarthritis, osteoporosis, regional disorders (spine, knee, shoulder, upper extremity, foot/ankle) bone, joint and soft tissue problems, nerve entrapments, chronic pain and related conditions. The program supports training in a range of complementary disciplines including epidemiology, biostatistics, pharmacoepidemiology, decision sciences, economic analysis, health disparities and behavioral interventions. This application requests funding for two predoctoral and three postdoctoral training positions per year. The trainees spend at least two years in the program. Those without prior formal didactic training obtain a master's degree in the Clinical Effectiveness Program at Harvard School of Public Health. The faculty includes outstanding mentors from Harvard Medical School, Harvard School of Public Health, Brigham and Women's Hospital and other Harvard medical institutions. The faculty members conduct research on a wide range of clinical areas and methodological disciplines. In its initial funding period, the COMET T32 program has begun to fulfill the need for clinical research training opportunities in musculoskeletal disorders. This renewal application builds upon the program's early successes and furthers the overarching programmatic goal of facilitating research to improve the quality of life of persons with musculoskeletal disorders.