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中文摘要
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描述(由申请人提供):埃默里神经系统紧急情况治疗试验-东南协作(NETT-SEC)是NETT网络的一个富有成效的成员。NETT-SEC参与了所有的NETT试验,在RAMART、ALIAS和ProTECT III的入组中排名前1/3,超过148例受试者入组了NETT试验(截至2011年11月14日)。NETT-SEC的目标与NETT的总体目标是同步的:在广泛的神经系统紧急情况中进行大型精简的III期临床试验,以降低神经系统疾病的发病率和死亡率。我们参与了所有NETT研究,并贡献了来自所有种族和民族的儿科和成人受试者。NETT-SEC与急诊医学、神经病学、神经重症监护、介入神经放射学、放射学、神经外科、麻醉学、创伤外科、药理学、伦理学、生物医学工程、实验室科学、神经心理学、神经眼科学、骨科(脊柱)、EMS、工业(Banyan Biomarkers)等形成了广泛而高度功能性的合作。此外,NETT-SEC汇集了大量的大容量城市和郊区医院,这些医院在多种族地区进行神经系统紧急情况开创性研究方面拥有良好的专业知识和经验记录。 目标:1.在NETT申办的临床试验中继续高水平招募多样化的受试者;通过扩大合作、培训计划、学生和教师指导以及社区外展来发展NETT-SEC; 3.通过加强NETT业务,扩大NETT研究组合,促进研究伦理对话,并向社区传播发现,促进神经系统紧急情况研究。NETT-SEC作为第一个NETT网络的生产中心有着良好的记录,并将继续通过进行高质量、高效率的工作来支持NETT和NINDS的目标。在学术和社区环境中进行的III期临床试验。
英文摘要
DESCRIPTION (provided by applicant): The Emory Neurological Emergencies Treatment Trials - Southeastern Collaborative (NETT-SEC) is a productive member of the NETT network. The NETT-SEC has participated in all NETT trials and is in the top 1/3rd for enrollments in RAMPART, ALIAS, and ProTECT III, accounting for over 148 subjects enrolled into the NETT trials (as of 11/14/2011). The goal of the NETT-SEC is synchronous with the NETT's overall stated purpose: to conduct large streamlined phase III clinical trials in a broad spectrum of neurological emergencies in order to reduce the morbidity and mortality of neurological diseases. We have participated in all of the NETT studies and contributed pediatric and adult subjects from all races and ethnicities. The NETT-SEC has formed extensive and highly functional collaborations with emergency medicine, neurology, neurointensive care, interventional neuroradiology, radiology, neurosurgery, anesthesiology, trauma surgery, pharmacology, ethics, biomedical engineering, laboratory science, neuropsychology, neuro-ophthamology, orthopedics (spine), EMS, Industry (Banyan Biomarkers), and others. In addition, the NETT-SEC brings together an extensive array of high volume urban and suburban hospitals with a well-established track record of expertise and experience in conducting ground-breaking research in neurological emergencies in a multiracial region. AIMS: 1.Continue high enrollment of a diverse population of subjects in NETT-sponsored Clinical Trials; 2. Grow the NETT-SEC by expanding collaborations, training programs, student and faculty mentoring, and community outreach; 3. Facilitate neurological emergencies research by enhancing NETT operations, expanding the NETT research portfolio, contributing to the dialog on research ethics, and disseminating discoveries to the community. The NETT-SEC has a proven track record as a productive hub of the first NETT network and will continue to support the goals of the NETT and NINDS by conducting high quality, efficient. Phase III clinical trials in both academic and community settings.
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ProTECT III
  • 批准号:
    8323400
  • 项目类别:
  • 资助金额:
    $638.62万
  • 财政年份:
    2009
  • 负责人:
    DAVID W WRIGHT
  • 依托单位:
ProTECT III
  • 批准号:
    8499434
  • 项目类别:
  • 资助金额:
    $50.85万
  • 财政年份:
    2009
  • 负责人:
    DAVID W WRIGHT
  • 依托单位:
ProTECT III
  • 批准号:
    8113157
  • 项目类别:
  • 资助金额:
    $833.03万
  • 财政年份:
    2009
  • 负责人:
    DAVID W WRIGHT
  • 依托单位:
ProTECT III
  • 批准号:
    7878810
  • 项目类别:
  • 资助金额:
    $886.71万
  • 财政年份:
    2009
  • 负责人:
    DAVID W WRIGHT
  • 依托单位:
海外基金