Research Career Development Core

项目概述：RCDC的首要任务是培养老龄化研究领域的未来领导者，专注于加州大学洛杉矶分校的主题领域，预防弱势群体的疾病和残疾：一种转化方法。RCDC将促进研究这一主题的未来研究领导者的发展，特别是那些能够将老年人的健康、疾病、独立和残疾的临床见解与基础科学（包括老年学）的进步知识结合起来的领导者，以开发更好的干预措施，以保持健康和独立。RCDC的目标是：1)确定最有潜力成为老龄化研究领域未来领导者的年轻教师，获得为期三年的职业发展奖（cda），重点关注我们的OAIC主题；2)培养这些青年科学家的科研训练和事业；3)为CDA获奖者提供一个支持性的环境，最大限度地提高他们成功培训、研究进展和最终职业成功的可能性；4)包括与每位受训者需求相关的转化科学原理和方法的培训；5)为加州大学洛杉矶分校青年教师提供老年相关研究指导资源。为了实现这些目标，加州大学洛杉矶分校RCDC还将对少数族裔CDA候选人进行外展，寻找受过临床培训的候选人，并注意少数族裔在研究中的重要性。一年级的4名候选cda正在进行与UCLA主题相关的研究。医学博士Jordan Lake是一名传染病专家，他正在研究慢性炎症加速hiv感染者衰老过程的机制。Judith Carroll博士是一位健康心理学家和心理神经免疫学家，她的工作重点是将睡眠作为一种模型来确定社会、情感、环境和行为因素对年龄相关疾病、免疫衰老和加速衰老的易感性的生物学机制。医学博士Lee Jennings是一名老年医学专家，他正在研究感染艾滋病毒的老年人的卫生保健需求，目的是提高对感染艾滋病毒的老年人的护理质量、获取和提供。Gerardo Moreno医学博士是一名家庭医生，他正在检查患有慢性病的脆弱老年人的适当药物管理和干预措施，包括决策支持和临床药师咨询，以改善初级保健机构的药物管理。

PROJECT SUMMARY (See instructions): The overarching mission of the RCDC is to develop future leaders in aging research, focused in the area of UCLA's theme, Preventing Disease and Disability in Vulnerable Populations: a Translational Approach. The RCDC will promote the development of future research leaders who address this theme, particularly leaders who can integrate clinical insights regarding health, disease, independence, and disability in older adults with knowledge of advances in the basic sciences, including gerontology, to develop better interventions to maintain health and independence. The goals of the RCDC are to 1) identify junior faculty who have the greatest potential as future leaders in aging research to receive three year career development awards (CDAs), focused on our OAIC theme; 2) foster the research training and careers of these junior scientists; 3) provide a supportive environment for CDA awardees that maximizes the likelihood of successful training, research progress and ultimate career success; 4) Include training in translational science principles and methods relevant to each trainee's needs; and 5) serve as a resource in aging-related research mentorship for UCLA junior faculty. In meeting these goals, the UCLA RCDC will also conduct outreach to minority CDA candidates, seek out candidates who have been clinically trained, and be attentive to the importance of minority populations' representation in research. The 4 candidate CDAs for Year 1 are conducting research related to UCLA's theme. Jordan Lake, MD, is an infectious disease specialist who is examining mechanisms by which chronic inflammation accelerates aging processes in HIV-infected persons. Judith Carroll, PhD, is a health psychologist and psychoneuroimmunologist whose work focuses on using sleep as a model to identify the biological mechanisms through which social, emotional, environmental and behavioral factors influence vulnerability for age-related disease, immunosenescence, and accelerated aging. Lee Jennings, MD, is a geriatrician who is examining the health care needs of older adults with HIV with the aims of improving the quality, access to and delivery of care to older persons with HIV. Gerardo Moreno, MD, is a family physician who is examining appropriate medication management among vulnerable older adults with chronic conditions and interventions including decision support, and clinical pharmacist consultations to improve medication management in primary care settings.