Northwestern University Allergy Immunology Research Program (NUAIR)

 描述（由申请人提供）：西北大学过敏免疫学研究（NUAIR）计划的总体目标是培养博士后科学家进行转化研究，这里定义为疾病机制的研究，包括对人类受试者或人类样本的调查。NUAIR计划建立在我们的过敏免疫学奖学金的基础上，该奖学金在临床和学术培训方面具有悠久的历史。在我们的司与其他部门和部门建立的研究人员的统一努力创造了一个丰富的环境，在NUAIR程序中，临床和基础研究人员，教师和学员，每周的研究和教学活动中进行合作和互动的转化研究。这些合作导致了在装备精良的实验室和大量的研究核心和设施的支持下，在几种过敏性疾病中的多学科转化研究计划。根据NUAIR计划，每年4名MD和/或博士研究生学员的稳定状态将接受2年的研究培训。每个人将与一名临床研究导师和一名基础研究导师合作，研究过敏性和免疫性疾病的机制，包括对人类受试者或其衍生样本的研究。除了结构良好的研究、培训和教学活动外，根据里程碑对学员的表现进行强有力的指导和密切监测，将确保培训期间取得适当进展。在第一个资助期内，我们指导了6名学员;完成的三名学员都已进入学术或行业研究职位。我们的保留计划包括支持学员谁留在我们的司作为初级教师后，T32支持的培训，而他们寻求外部资金支持。过敏免疫学系的高级教师在指导学员获得K奖（目前有5名）和新的R 01赠款（4名初级教师）方面有着良好的记录。我们还提供计划，以激励医学生和居民追求过敏免疫学的职业生涯。总的来说，我们迅速扩大和全面的过敏免疫学研究环境将提供最先进的培训，以高素质的医学博士，医学博士/博士和博士博士后学员。这些学员将进行过敏方面的合作转化研究- 免疫学，启动研究事业，这将有助于解决在这一领域的学术领导人严重的国家需求。

 DESCRIPTION (provided by applicant): The overall aim of the Northwestern University Allergy-Immunology Research (NUAIR) Program is to train postdoctoral scientists in translational research, here defined as research of disease mechanisms that includes investigations in human subjects or human samples. The NUAIR Program builds on our Allergy-Immunology Fellowship, which has a long history of excellence in clinical and academic training. Unified efforts of established investigators in our Division with those from other Divisions and Departments have created a rich environment for translational research in the NUAIR program in which clinical and basic researchers, both faculty and trainees, collaborate and interact in weekly research and didactic activities. These collaborations have led to multidisciplinary translational research programs in several allergic diseases supported by well- equipped laboratories and a large number of research cores and facilities. Under the NUAIR Program, a steady state of 4 MD and/or PhD postgraduate trainees per year will receive 2 years of research training. Each will work together with a clinical research mentor and a basic research mentor to study mechanisms of allergic and immunological diseases, including studies of human subjects or their derived samples. In addition to well- structured research training and didactic activities strong mentoring and close monitoring of trainees' performances based on milestones will ensure proper progress during training. During the first period of funding, we have mentored 6 trainees; the three who have finished have all gone on to academic or industry research positions. Our retention plan includes support for trainees who remain in our Division as junior faculty members after T32-supported training, while they seek external funding support. Senior faculty members in the Allergy-Immunology Division have a strong record of mentoring trainees towards obtaining K awards (5 currently) and new R01 grants (4 junior faculty). We also offer programs to inspire medical students and residents to pursue careers in Allergy-Immunology. Taken together, our rapidly expanding and comprehensive Allergy-Immunology research environment will provide state-of-the-art training to highly qualified MD, MD/PhD and PhD postdoctoral trainees. These trainees will conduct collaborative translational research in Allergy- Immunology, initiating research careers that will help solve a severe national need for academic leaders in this field.