Immunology Research Training Grant

摘要 要求在新的培训补助金中支持四个职位，以继续和扩大我们成功的 加州大学欧文分校（UCI）的免疫学培训项目。我们共有36位导师， 包括初级、中级和高级培训教员，其中包括14名妇女和3名城市资源管理教员。UCI免疫 研究人员正在研究：a）宿主防御和疫苗开发; B）肿瘤免疫学和 d）慢性疾病和自身免疫;以及 d）合成免疫学。免疫学研究生的池主要来自细胞和 分子生物学（CMB）摄入计划。2022年，中巴录取101名学生，其中URM 39名 (38.6%），平均绩点为3. 86（与二零二零年及二零二一年相若）。有大量的机构 研究办公室和UCI研究生部的支持，将提供全额奖学金， 第五名学生的学费。我们之前的T32从2016-2021支持15名学生，其中大部分已经毕业 并在工业界或学术界担任研究职位。Eric Pearlman博士是UCI研究所所长， 免疫学，是以前的T32培训补助金的主要研究者。在本报告中， 博士Pearlman将担任PI/主任，新招聘的教师Ivan Marazzi博士将担任联合主任。珀尔曼医生 在培养研究生和运行T32赠款方面有丰富的经验，Marazzi博士有非常 令人兴奋的和资金充足的研究计划，在自身免疫慢性神经退行性疾病， 分子病毒学，包括流感和新冠肺炎。考虑到教师的出色培训记录和 质量的培训补助elibile和URM的学生在该计划中，我们完全预计，UCI免疫学 培训计划将继续为下一个提供出色的教育和职业机会 一代免疫学研究者。

ABSTRACT Support is requested for four positions in a new training grant to continue and expand our successful Immunology Training Program at the University of California, Irvine (UCI). We have a total of 36 mentors that include junior, mid-level and senior training faculty comprising 14 women and 3 URM faculty. UCI immunology researchers are working on: a) host defense and vaccine development; b) tumor immunology and immunotherapy; c) Neurogenerative disease and microglia biology; d) chronic diseases and autoimmunity; and d) synthetic immunology. The pool of immunology graduate students comes primarily from the Cellular and Molecular Bology (CMB) intake program. In 2022, 101 students were accepted to CMB, including 39 URM (38.6%), and their mean GPA was 3.86 (which was similar to 2020 and 2021). There is substantial institutional support from the Office of Research and from the Graduate Division at UCI, which will provide full stipend and tuition for a 5th student. Our prior T32 from 2016-2021 supported 15 students, most of whom have graduated and are in research positions in industry or academia. Dr. Eric Pearlman is the Director of the UCI Institute for Immunology and was the Prinicipal Investigator of the previous T32 training grant. In the current submission, Dr. Pearlman will be PI/Director, and a new faculty recruit, Dr. Ivan Marazzi, will be co-Director. Dr. Pearlman has extensive experience in training graduate students and running T32 grants, and Dr. Marazzi has a very exciting and well funded research program in autoimmunity chronic neurodegenerative diseases and in molecular virology, including influenza and COVID-19. Given the outsanding training record of faculty and the quality of training grant elibile and URM students in the program, we fully anticipate that the UCI Immunology training program will continue to provide outstanding educational and career opportunities for the next generation of immunology researchers.