Bioconductor: An Open Computing Resource for Genomics

 描述(申请人提供)：BioConductor是一个致力于分析和理解高通量基因组(序列、微阵列、流式细胞仪、蛋白质组学、成像)数据的项目。BioConductor是基于R统计编程语言的。它包括由这笔赠款资助的个人以及国家和国际科学界开发和贡献的软件、注释和“实验数据”包。BioConductor备受推崇，在全球生物信息界得到广泛应用，并被高度引用。该项目的具体目标反映了BioConductor模型：(1)突破性的统计软件开发(资源项目核心)和(2)强大的核心和贡献的软件储存库和支持基础设施，以将相对适度的资金放大到学术、政府和行业生物医学研究的广泛领域的高效投资中。该项目的最终目标是(3)有效和长期的项目管理、传播和培训，将许多学生转变为科学专业人员和天真的软件用户，成为统计基因组学领域的老练领导者。

 DESCRIPTION (provided by applicant): Bioconductor is a project dedicated to the analysis and comprehension of high throughput genomic (sequence, microarray, flow cytometry, proteomics, imaging) data. Bioconductor is based on the R statistical programming language. It consists of software, annotation, and `experiment data' packages developed and contributed by individuals funded by this grant, and by the national and international scientific community. Bioconductor is highly respected, widely used in the global bioinformatics community, and highly cited. The specific aims of this project reflect the Bioconductor model of (1) ground-breaking statistical software development (Resource Project Core) and (2) robust core and contributed software repository and support infrastructure to amplify relatively modest funding into highly-effective investment in broad areas of academic, government, and industry biomedical research. The final aim of the project is (3) effective and long-term project administration, dissemination, and training to transform many students into scientific professionals, and naive software users, into sophisticated leaders in statistical genomics.