Washington University Center for Diabetes Translation Research

项目摘要 华盛顿大学糖尿病翻译研究中心(WU-CDTR)的使命是 通过翻译、传播、实施和维持循证医学来消除糖尿病方面的差异 将研究成果转化为现实世界的环境。WU-CDTR位于一所优秀的机构，继续 作为一群从事严格翻译研究的特殊研究人员的智力家园 重点围绕两个相互作用的科学主题：(1)糖尿病差异的根本原因，和(2) 预防肥胖是导致2型糖尿病的主要原因。WU-CDTR已经演变成 一个“网络网络”，调查人员通过与加州大学的区域资源核心联系在一起 哥伦比亚的密苏里州，以及美国国会的两个健康差距人口核心 印第安人和非裔美国人肥胖合作研究网络。WU-CDTR养育 跨学科协作，催生新想法，并通过六个研究核心支持调查人员 由各自领域的国家专家提供独特但互补的科学专业知识 向处于差异风险人群中的研究提供信息，包括：(1)在 糖尿病研究核心，推进糖尿病传播与实施科学研究 (2)糖尿病研究核心中的政策和系统科学分析，推进了研究 糖尿病研究中的政策和系统层面的干预；(3)健康传播和健康 扫盲核心，它推动健康传播科学的研究，以测试应对战略 糖尿病研究中的健康差异；(4)糖尿病研究核心中的健康信息学，它促进了 医疗保健信息学在转化型糖尿病研究中的发展和应用；(5)研究 与美国印第安人/阿拉斯加原住民社区核心的伙伴关系，这增加了 研究人员与美国印第安人和阿拉斯加原住民社区进行翻译研究；以及(6) 美国黑人糖尿病的解决方案核心，提供方法和内容专业知识，以 支持对黑人人口的研究。WU-CDTR支持充满活力的试点和可行性计划 旨在吸引和留住新的调查人员以及新进入该领域的现有调查人员；它还 支持丰富计划，促进跨学科研究、学习机会和 为年轻的调查人员提供指导。吴-CDTR成功执行任务的证据 包括在糖尿病和相关领域的出版物和资金中反映的杰出生产力的记录 研究。成功也是通过我们现有的和新的糖尿病研究基础的增长来衡量的 调查人员，以及代表不足的少数族裔调查人员。WU-CDTR被定位为 跨学科团队科学和变革性糖尿病研究解决多个维度 糖尿病差异。

Project Summary The mission of the Washington University Center for Diabetes Translation Research (WU-CDTR) is to eliminate disparities in diabetes by translating, disseminating, implementing, and sustaining evidence-based research findings into real-world settings. The WU-CDTR is located at an outstanding institution that continues as the intellectual home to an exceptional group of investigators conducting rigorous translational research focused around two interacting scientific themes: (1) the root causes of diabetes disparities, and (2) the prevention of obesity as a major contributing cause of Type 2 diabetes. The WU-CDTR has evolved to become a ‘network of networks’, with investigators affiliated through a regional resource core with the University of Missouri at Columbia, and two health disparity population cores with the National Congress of American Indians, and the African American Collaborative Obesity Research Network. The WU-CDTR fosters transdisciplinary collaborations, catalyzes new ideas, and supports investigators through six research cores led by national experts in their respective fields that provide distinctive but complementary scientific expertise to inform research with populations at risk for disparities, including: (1) the Dissemination and Implementation in Diabetes Research Core, which advances the study of dissemination and implementation science in diabetes research; (2) the Policy and Systems Science Analysis in Diabetes Research Core, which advances the study of policy- and system-level interventions in diabetes research; (3) the Health Communication and Health Literacy Core, which advances the study of health communication science to test strategies for addressing health disparities in diabetes research; (4) the Health Informatics in Diabetes Research Core, which advances the development and application of healthcare informatics in translational diabetes research; (5) the Research Partnerships with American Indian/Alaska Native Communities Core, which increases the capacity of researchers to engage in translational research with American Indian and Alaska Native communities; and (6) the Solutions to Diabetes in Black Americans Core, which provides methodological and content expertise to support research with the Black population. The WU-CDTR supports a vibrant Pilot and Feasibility Program designed to attract and retain new investigators as well as established investigators new to the field; and it also supports an Enrichment Program that promotes transdisciplinary research, learning opportunities, and mentorship for young investigators. Evidence that the WU-CDTR has been successful in pursuing the mission includes a record of outstanding productivity reflected by publications and funding in diabetes and related research. Success is also measured by the growth of our research base of established and new diabetes investigators, and underrepresented racial minority investigators. The WU-CDTR is positioned as the nexus for transdisciplinary team science and transformative diabetes research addressing multiple dimensions of diabetes disparities.