UC San Diego Clinical and Translational Research Institute

项目摘要 我们已经建立了加州大学圣迭戈分校临床和翻译研究所(CTRI)，其中心位于 加州大学圣地亚哥分校(UCSD)。该区域中心包括三所大学(加州大学圣迭戈分校、圣地亚哥分校 州立大学和加州大学河滨分校)，4个生物医学研究所(索尔克研究所，桑福德-伯纳姆研究所， J.克雷格·文特尔研究所和拉霍亚过敏和免疫学研究所)和3家学术医院(加州大学圣迭戈分校 医疗中心、退伍军人圣地亚哥医疗中心和拉迪儿童医院)，一个社区卫生中心 (Palomar Health)。CTSA计划包括3所健康科学专业学校(医学、 药学和护理学)和2个临床研究和药物发现科学硕士课程。这个 计划的目标是：1)制定跨翻译科学的综合教育和培训计划 SPECTRUM；2)增强基于社区的合作伙伴关系，并将利益相关者纳入翻译 研究治理；3)多样化和增强生物医学信息学基础设施，以提供安全、 机密性和互操作性平台；4)提供管理和改进的行政基础设施 临床和转化性研究；以及5)提供资源，加强协作，鼓励颠覆性 创新和支持临床研究。CTSA计划，将设在新的Altman CTRI 建设，将提供资源，以发展临床和转化研究的学科，改善 研究质量和效率，确保多样化的劳动力管道，并支持协作和 团队科学。加州大学圣迭戈分校CTRI将把加州大学河滨分校纳入其TL1计划和圣地亚哥州 将大学护理和公共卫生学院纳入其KL2计划，以增加学科的多样性 以及实习生的背景。一个新的寿命研究中心将支持对寿命的研究 在特殊人群中。生物医学信息学专业知识将用于帮助管理临床研究和 分析新数据，包括加速药物中心扩大的I期生物标志物单位 发展。UCSD CTRI将通过与其他CTSA中心合作来利用其资源，包括 加州大学学校联盟(UC Braid)和更广泛的CTSA网络。

Project Abstract We have established the UCSD Clinical and Translational Research Institute (CTRI), with its hub located at the University of California, San Diego (UCSD). This regional center includes three universities (UCSD, San Diego State University and UC Riverside), 4 biomedical research institutes (Salk Institute, Sanford-Burnham Institute, J. Craig Venter Institute, and La Jolla Institute for Allergy and Immunology), and 3 academic hospitals (UCSD Medical Center, VA San Diego Medical Center and Rady Children's Hospital), one community health center (Palomar Health). The CTSA program encompasses 3 health sciences professional schools (Medicine, Pharmacy, and Nursing) and 2 Master's programs in Clinical Research and Drug Discovery Sciences. The program goals are to: 1) Develop an integrated education and training program across the translational science spectrum; 2) Empower community-based partnerships and integrate the stakeholders into translational research governance; 3) Diversify and enhance biomedical informatics infrastructure to provide a secure, confidential and inter-operative platform; 4) Provide administrative infrastructure to manage and improve clinical and translational research; and 5) Provide resources that enhance collaboration, encourage disruptive innovation and support clinical investigation. The CTSA program, which will be housed in the new Altman CTRI building, will provide the resources to develop the discipline of clinical and translational research, improve research quality and efficiency, assure a diverse workforce pipeline, and support a culture of collaboration and team science. The UCSD CTRI will incorporate UC Riverside into its TL1 program and San Diego State University Schools of Nursing and Public Health into its KL2 program to increase the diversity of disciplines and backgrounds of trainees. A new Center for Lifespan Research will support investigation across the lifespan and in special populations. Biomedical informatics expertise will be used to help manage clinical research and analyze new data, including the expanded phase I biomarker unit in the Center for Accelerating Drug Development. The UCSD CTRI will leverage its resources by collaborating with other CTSA hubs, including the consortium of UC schools (UC BRAID) and the broader CTSA network.