Rickettsiales: Host-Vector-Pathogen Interactions
Rickettsiales: Host-Vector-Pathogen Interactions
批准号:
9193259
负责人:
Jason A Carlyon
金额:
$0.7万
依托单位国家:
美国
项目类别:
财政年份:
2016
资助国家:
美国
项目状态:
已结题
起止时间:
2016-06-11 至 2017-05-31
关键词:
AcademiaAcademyAcuteAddressAdmission activityAmericanAnimal ModelArthropod VectorsArthropodsBacteriaBiologyBloodBovine AnaplasmosisCase StudyCellular biologyChiggersChildChild CareCommittee MembersCommunicable DiseasesDengue VirusDevelopmentDiagnosisDiagnosticDisciplineDiseaseEducational workshopEnabling FactorsEnsureEpidemiologyFeverFleasFosteringGenomicsGoalsGovernmentGrantHealthHospitalizationHospitalsHumanImmunologyIndustryInfectionInstitute of Medicine (U.S.)Intensive CareKnowledgeKoreansLeadLiceLifeLocationLyme DiseaseLymphMalariaMeasuresMolecular BiologyMontanaMorbidity - disease rateOralParticipantPatientsPlayPreventionProductionPublicationsRecording of previous eventsRecruitment ActivityReportingResearchResearch PersonnelResolutionResortRickettsiaRickettsia InfectionsRickettsialesRiskRocky Mountain Spotted FeverRoleScienceScientistServicesSiteSocietiesTick-Borne DiseasesTick-Borne InfectionsTicksTranslatingTravelUnderrepresented GroupsUnited States National Institutes of HealthUniversitiesVaccinesVector-transmitted infectious diseaseVietnam ConflictVisualWarWest Nile virusWomanWorld War IIbiothreatcareercostdisabilityfeedingimmunopathologyimprovedinterestlecturesmedical schoolsmeetingsmortalityneglectneglected tropical diseasesnovelpathogenposterspreventprogramssymposiumvaccinologyvector
中文摘要
研讨会摘要:立克次体疾病:宿主-病原体-载体的相互作用
立克次体病是发病率和死亡率的重要原因。他们负责大多数
所有蜱虫传播的感染中的入院率、重症监护室入院率和死亡率。许多正在涌现
或重新出现,具有生物威胁影响,和/或被忽视。立克次体疾病一直是
造成数百万人死亡,是仅次于疟疾的第二大部队发热性疾病。
第二次世界大战、朝鲜战争和越南战争。没有任何立克次体病的疫苗存在,
这些细菌与其节肢动物载体和哺乳动物宿主的相互作用尚不清楚。填充这种
知识缺口将提高对立克次体病理学的理解,
治疗。事实上,2011年国家科学院医学研究所研讨会报告,"关键需求
以及在理解、预防、改善和解决莱姆病和其他蜱媒疾病方面的差距"
强调,了解这些病原体的因素,使他们能够生存和导致疾病,
从而导致新对策发展。 预防立克次体挑战的复杂性
疾病是由于,至少部分,病原体之间的进化关系,他们的节肢动物
载体和哺乳动物宿主。美国立克次体学会(ASR)有着悠久的历史,
促进世界知名专家之间科学互动和丰富知识交流的论坛,
立克次体病 第28届ASR会议将于2016年6月11日至2016年12月14日在蒙大拿州的大天空举行。
大约200名与会者代表来自学术界、政府和
工业是预期的。会议的首要目标是促进知识和刺激互动
通过讲座、简短的口头报告、海报会议和网络,
机会 为了解决上述知识差距,我们建议在
在题为"立克次体病:宿主-传播媒介-病原体相互作用"的第28次会议框架内, 的
研讨会的目的是(i)提供一个论坛,促进与会者和专家之间的科学交流
通过邀请领导和初级研究人员的主题演讲和全体会议、简短的会谈和海报,
研究立克次氏体和其他媒介传播疾病; 2(ii)提供一个展示最新、最先进的
研究立克次氏体病和其他由节肢动物引起的疾病-寄生/专性细胞内病原体;
提供一个场所,促进初级和高级之间的知识交流和网络机会
㈣促进职业生涯初期和任职人数不足的人员的参与
生物医学科学,包括女性。还将努力为需要的与会者提供住宿,
儿童看护。要求为研讨会提供支助,以支付协调、设施、
特邀讲者和选定的与会者,以及视听服务和节目制作。
英文摘要
Workshop Summary: Rickettsial Diseases: Host-Vector-Pathogen Interactions
Rickettsial diseases are significant causes of morbidity and mortality. They are responsible for the majority of
hospital admissions, intensive care admissions, and fatalities among all tick-borne infections. Many are emerging
or re-emerging, have biothreat implications, and/or are neglected. Rickettsial diseases have been responsible
for the loss of millions of lives and were second only to malaria as the cause of febrile illness among troops in
World War II, the Korean War, and the Vietnam Conflict. No vaccine for any rickettsial disease exists, and the
interactions of these bacteria with their arthropod vectors and mammalian hosts are poorly defined. Filling such
knowledge gaps will improve understanding of rickettsial pathobiology and promote development of novel
treatments. Indeed, the 2011 Institute of Medicine of the National Academies workshop report, “Critical needs
and gaps in understanding, prevention, amelioration, and resolution of Lyme and other tick-borne diseases”
emphasized that understanding these pathogens’ factors that enable them to survive and cause disease would
lead to development of novel countermeasures. The complexity of the challenge of preventing rickettsial
diseases is due, at least in part, to the evolutionary relationships between the etiologic agents, their arthropod
vectors, and mammalian hosts. The American Society for Rickettsiology (ASR) has a long history of providing
forums that foster scientific interactions and rich intellectual exchange among world-renowned experts on
rickettsial diseases. The 28th Meeting of the ASR will be held June 11-14, 2016 in Big Sky, Montana.
Approximately 200 attendees representing junior and established scientists from academia, government, and
industry are anticipated. The conference’s overarching goal is to advance knowledge and stimulate interactions
among these researchers through lectures, short oral presentations, poster sessions, and networking
opportunities. To address the aforementioned knowledge gap, we propose a small workshop within the
framework of the 28th meeting entitled, “Rickettsial Diseases: Host-Vector-Pathogen Interactions.” The
workshop’s aims are to (i) provide a forum that promotes scientific exchange among participants and experts
through invited keynote and plenary lectures, short talks, and posters by leaders and junior investigators that
study rickettsial and other vector-borne diseases;; (ii) offer a program that presents the latest, cutting-edge
research of rickettsial and other diseases caused by arthropod-borne/obligate intracellular pathogens;; (iii)
provide a venue that fosters intellectual exchange and networking opportunities between junior and senior
investigators;; and (iv) promote participation by those that are early in their careers and that are underrepresented
in the biomedical sciences, including women. Efforts will also be made to accommodate attendees in need of
child care. Support for the workshop is requested to cover the cost of coordination, facilities, travel expenses for
invited speakers and selected attendees, and for audio-visual services and program production.
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海外基金