Plasma lipidomic signatures for risk prediction and prevention of gestational diabetes

每年有超过20，000名澳大利亚妇女患上妊娠糖尿病（GDM），增加了她们患妊娠并发症以及糖尿病和心脏病的风险。脂质是细胞能量的关键来源，在怀孕期间经常发生变化，但它们在GDM中的作用尚不清楚。使用新的技术，我将测量数百种脂质，以检查某些脂质种类是否有助于GDM的发展，以及这些脂质是否被饮食，生活方式和/或药物治疗改变。

Over 20,000 Australian women develop gestational diabetes (GDM) annually, increasing their risk of pregnancy complications, as well as diabetes and heart disease later in life. Lipids are a key source of energy for cells and often change during pregnancy, yet their role in GDM is unknown. Using novel techniques, I will measure hundreds of lipids to examine whether certain lipid species contribute to GDM development and whether these lipids are altered by diet, lifestyle, and/or drug therapies.