Plasmapheresis as a Novel treatment of Postural Tachycardia Syndrome: a randomised controlled trial

我们的目标是进行一项随机对照试验来验证我们的假设，即去除自身抗体（通过血浆置换）将减轻体位性心动过速综合征患者症状的严重程度。我们将测量症状评分、运动测试中的心血管健康、valsalva和体位压力期间的心率和血压反应，以及参与试验的患者血液中的代谢谱和自身抗体的存在。

We aim to conduct a randomized controlled trial to test our hypothesis that the removal of autoantibodies (through plasmapheresis) will reduce the severity of symptoms in patients with postural tachycardia syndrome. We will be measuring symptom scores, cardiovascular fitness on exercise testing, heart rate and blood pressure responses during valsalva and orthostatic stress as well as the metabolic profiles and presence of autoantibodies in the blood of patients participating in the trial.