Cognitive neuroscience of spatial asymmetry: behaviour, genes and brain imaging

当人类在空间中分配注意力时，存在空间注意力的偏向或不对称性。健康的个体表现出有利于左侧空间的加工优势，但这种优势在单侧空间忽视、多动症和阅读障碍等障碍中消失。该项目将开发新的电生理学方法来分离感觉、注意力、决策和运动对空间不对称的贡献。通过将电生理学与遗传学、神经化学和脑成像方法相结合，该项目将全面绘制空间不对称的生物学图谱。这一知识对于开发有效的治疗空间不对称非典型模式导致神经脆弱性的疾病至关重要。

When humans distribute their attention in space, biases or asymmetries of spatial attention exist. Healthy individuals exhibit a processing advantage favouring left space but this advantage is lost in disorders such as unilateral spatial neglect, ADHD and dyslexia. This project will develop novel electrophysiological methods to dissociate the sensory, attentional, decision-making and motoric contributions to spatial asymmetries. By interfacing electrophysiology with genetic, neurochemical and brain imaging methods, this project will comprehensively map the biology of spatial asymmetry. This knowledge is vital to developing effective treatments for disorders where atypical patterns of spatial asymmetry index neurological vulnerability.