Preclinical Studies in Xenotransplantation

许多器官衰竭的人需要移植才能生存。不幸的是，大多数可以从移植手术中受益的病人都无法接受移植手术，因为活着的或死去的捐赠者短缺。一个可能的解决办法是使用动物器官。猪是最合适的动物供体。该项目旨在生产和测试转基因猪，这些猪在移植到人体受体时可以提供抵抗排斥反应的器官。

Many people with organ failure need a transplant to survive. Unfortunately most patients who would benefit from a transplant are unable to receive one because of the shortage of living or deceased donors. A possible solution to this shortage is to use animal organs. Pigs are the most suitable animal donor. This project aims to produce and test genetically modified pigs which can provide organs that will be resistant to rejection when transplanted into human recipients.