Probiotic Prawn Oral Immunotherapy (ProPIT) for Treatment of Prawn Allergy

为了防止死亡和改善护理，需要一种“根治性”的食物过敏治疗。我们最近发现益生菌花生口服免疫疗法(PPOIT)治疗花生过敏是非常有效的。82%的接受PPOIT治疗的儿童获得了耐受性，而安慰剂组的这一比例为4%。我们现在将测试益生菌-食物OIT联合治疗对虾过敏的方法。如果成功，我们将确定第一种对虾过敏疗法和一种治疗其他食物过敏的平台疗法。

A ‘curative’ food allergy treatment is needed to prevent deaths and improve care. We recently showed that probiotic peanut oral immunotherapy (PPOIT) was highly effective for treating peanut allergy. 82% of PPOIT treated children gained tolerance compared to 4% of the placebo group. We will now test the combined probiotic-food OIT approach for treating prawn allergy. If successful, we will have identified the first treatment for prawn allergy and a platform treatment for other food allergies.