Altered Myelin Sphingolipid Homeostasis in Alzheimer's Disease

阿尔茨海默病（AD）是最常见的痴呆症，随着人口老龄化，其发病率正在上升。该项目将详细分析和解释AD患者大脑中对髓磷脂完整性至关重要的特定脂质（脂肪）分子的损失。髓磷脂是包裹在脑细胞周围的绝缘层，促进电信号的传递。这项研究将提高我们对AD患者大脑功能受损的理解。

Alzheimer’s Disease (AD) is the most common form of dementia, and its incidence is rising as the population ages. This project will provide a detailed analysis and explanation for the loss of particular lipid (fat) molecules that are essential for myelin integrity, in the brains of AD patients. Myelin is the insulating layer that surrounds brain cells, facilitating the transmission of electrical signals. This research will improve our understanding of how brain functions are impaired in AD.