Rates of psychosis onset in a high risk population

早前对精神分裂症高危人群的研究发现，其中约35%的人在一年内患上了精神病。然而，这种风险最近已降至10%。他们可能仍然会变成精神病，但需要更长的时间，或者他们可能根本不会发展成精神病。我们需要对此进行研究，这样那些没有“风险”的人就不会得到不必要的治疗。我们将跟踪“有风险”的人，并确定他们6年的结果。我们会做扫描，看看是否有任何与精神病有关的大脑变化。

Older studies of people at risk of schizophrenia found that about 35% of them developed psychosis within 1 year. However the risk has decreased lately to as low as 10%. They may still become psychotic but take longer to do so, or they may not develop psychosis at all. We need to study this so that those not “at risk” are not needlessly treated. We will follow up “at risk” people and determine their 6 year outcome. We will do scans to see if there are any brain changes associated with psychosis.