Reducing the greatest uncertainty in radiotherapy.

放射治疗中最薄弱的环节是确定治疗量（轮廓）。临床试验轮廓缺乏准确性和一致性已被证明会导致患者预后降低。手工检查轮廓是资源密集的，昂贵的和先进的治疗无法及时实现。我们将使用4个临床试验数据集评估一种自动化的轮廓评估方法，为未来的研究改变实践，并在临床中实现一致的评估。

The weakest link in radiotherapy is defining treatment volumes (contouring). Lack of accuracy and consistency in clinical trial contouring has been shown to result in reduced patient outcomes. Manual review of contouring is resource intensive, expensive and for advanced treatments unachievable in a timely fashion. We will assess an automated approach to contouring assessment using 4 clinical trial datasets, changing practice for future studies and enabling consistent assessment in the clinic.