An investigation into the role of 3’UTR dynamics in breast cancer metastasis
An investigation into the role of 3’UTR dynamics in breast cancer metastasis
批准号:
nhmrc : GNT1128250
负责人:
A/Pr David Powell
金额:
$62.74万
依托单位:
依托单位国家:
澳大利亚
项目类别:
Project Grants
财政年份:
2017
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2017-01-01 至 --
中文摘要
基础研究给癌症的诊断和治疗带来了许多改进。三阴性乳腺癌是一个例外。目前还没有针对性的治疗方法,因此化疗、手术和放射治疗的组合是唯一的选择。对于2/3的女性来说,这种方法效果很好,存活率很高,但对于那些没有反应的女性来说,预后很差。这项研究旨在揭示阻止此类肿瘤扩散的治疗机会。
英文摘要
Basic research has brought many improvements to the diagnosis and treatment of cancer. An exception are the triple negative breast cancers. No targeted therapies yet exist, and thus a combination of chemotherapy, surgery and radiation therapy is the only option. For 2/3rds of women this works well and survivor rates are high, but the prognosis is poor for those that do not respond. This research aims to reveal therapeutic opportunities to block the potential of such tumours to spread.
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会议论文
Analysis of circulating tumour DNA for mutational characterisation and tracking disease progression in multiple myeloma
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批准号:nhmrc : GNT1142184
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项目类别:Project Grants
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资助金额:$90.87万
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财政年份:2018
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负责人:A/Pr David Powell
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依托单位:
海外基金