The ASPREE-fracture sub-study: Does daily low-dose aspirin reduce fracture risk in healthy older adults?

老年人骨折造成的残疾、死亡和医疗负担是全球日益严重的问题。尽管有数十年的临床研究，最佳实践指南和旨在降低骨折风险的治疗进展。世界卫生组织已将预防骨折确定为公共卫生优先事项。这项研究将确定是否广泛可用，简单和廉价的健康干预-阿司匹林-可以减少骨折和相关残疾的发生率在老年澳大利亚人。

Disability, mortality and healthcare burden from fractures in older people is a growing problem worldwide. This is despite decades of clinical research, best practice guidelines and advances in therapies that aim to reduce fracture risk. The World Health Organization has identified fracture prevention as a public health priority. This study will determine whether a widely available, simple and inexpensive health intervention—aspirin—can reduce the incidence of fracture and associated disability amongst older Australians.