The generation and function of tissue-specific regulatory T cells

免疫系统通常保护人体免受有害病毒和细菌等病原体的入侵。在自身免疫性疾病中，用来保护我们的相同机制被错误地瞄准了我们自己的组织。我们将发现调节性淋巴细胞如何能够预防自身免疫性疾病。这种调节性淋巴细胞是预防多种免疫介导疾病（包括自身免疫性疾病、过敏和移植排斥）的有吸引力的治疗药物。

The immune system normally protects against invasion by pathogens such as harmful viruses and bacteria. In autoimmune diseases the same mechanisms that are used to protect us are erroneously targeted to our own tissues. We will discover how regulatory lymphocytes, are able to protect against autoimmune disease. Such regulatory lymphocytes are attractive therapeutic agents to prevent a variety of immune-mediated diseases, including autoimmune diseases, allergy and transplantation rejection.