The molecular regulation of platelet life span

血小板过少会导致致命的出血，血小板计数低的患者需要输血以防止出血。我们最近发现了保持血小板存活的关键，现在提出了关键的实验，这将教会我们如何操纵它，让血小板活得更长。我们的团队在这个领域处于世界领先地位。如果成功，我们预计将改善血库血小板储存，并增加需要输血的患者可获得的血小板供应。

Too few blood platelets leads to fatal haemorrhage, and patients with low platelet counts require transfusions to prevent bleeding. We have recently discovered the key to keeping platelets alive, and now propose the critical experiments which will teach us how to manipulate it and allow platelets to live longer. Our team leads the world in this field. If successful we expect to improve blood bank platelet storage, and boost the supply of platelets available to patients in need of transfusion.