Translating advances in molecular oncology into improved care for patients with haematological malignancies

将分子肿瘤学的进步转化为改善血液恶性肿瘤患者的护理

• 批准号: nhmrc : GNT1079560
• 负责人: Prof Andrew Roberts
• 金额: $ 39.4万
• 依托单位国家: 澳大利亚
• 项目类别: Practitioner Fellowships
• 财政年份: 2015
• 资助国家: 澳大利亚
• 起止时间: 2015-01-01 至 无数据
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/translating-advances-molecular-haematological-malignancies/1345292
• 关键词: Translating; advances; molecular; oncology; into

The purpose of my research is to develop and integrate into routine practice better treatment paradigms for patients with blood cancers – leukaemias, lymphomas, myeloma. My research seeks to (i) bring a new class of anti-cancer targeted therapy, inhibitors of Bcl-2, into routine care; (ii) discover the genetic changes that explain why slow growing lymphoid cancers change into rapidly fatal lymphomas; and (iii) integrate new molecular tests into the management of patients with acute leukaemia.

我的研究目的是为血液癌患者（淋巴瘤，淋巴瘤，骨髓瘤）开发并融入常规实践更好的治疗范例。我的研究试图（i）将新的抗癌靶向疗法（BCL-2抑制剂）带入常规护理； （ii）发现遗传变化解释了为什么缓慢生长的淋巴癌转变为快速致命的淋巴瘤； （iii）将新的分子测试整合到急性白血病患者的管理中。