Translating advances in molecular oncology into improved care for patients with haematological malignancies

将分子肿瘤学的进步转化为改善血液恶性肿瘤患者的护理

• 批准号: nhmrc : GNT1079560
• 负责人: Prof Andrew Roberts
• 金额: $ 39.4万
• 依托单位国家: 澳大利亚
• 项目类别: Practitioner Fellowships
• 财政年份: 2015
• 资助国家: 澳大利亚
• 起止时间: 2015-01-01 至 无数据
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/translating-advances-molecular-haematological-malignancies/1345292
• 关键词: Translating; advances; molecular; oncology; into

The purpose of my research is to develop and integrate into routine practice better treatment paradigms for patients with blood cancers – leukaemias, lymphomas, myeloma. My research seeks to (i) bring a new class of anti-cancer targeted therapy, inhibitors of Bcl-2, into routine care; (ii) discover the genetic changes that explain why slow growing lymphoid cancers change into rapidly fatal lymphomas; and (iii) integrate new molecular tests into the management of patients with acute leukaemia.

我的研究目的是为血癌患者——白血病、淋巴瘤、骨髓瘤——开发更好的治疗模式，并将其纳入常规实践。我的研究旨在(i)将一类新的抗癌靶向治疗——Bcl-2抑制剂引入常规护理；（ii）发现解释为什么生长缓慢的淋巴样癌症转变为迅速致命的淋巴瘤的基因变化；（三）将新的分子检测纳入急性白血病患者的管理。