Translating advances in molecular oncology into improved care for patients with haematological malignancies

我研究的目的是为血癌患者（白血病、淋巴瘤、骨髓瘤）开发更好的治疗模式，并将其纳入常规实践。我的研究旨在（i）将一类新的抗癌靶向治疗，Bcl-2抑制剂，纳入常规护理;（ii）发现遗传变化，解释为什么缓慢生长的淋巴癌转变为快速致命的淋巴瘤;（iii）将新的分子检测纳入急性白血病患者的管理。

The purpose of my research is to develop and integrate into routine practice better treatment paradigms for patients with blood cancers – leukaemias, lymphomas, myeloma. My research seeks to (i) bring a new class of anti-cancer targeted therapy, inhibitors of Bcl-2, into routine care; (ii) discover the genetic changes that explain why slow growing lymphoid cancers change into rapidly fatal lymphomas; and (iii) integrate new molecular tests into the management of patients with acute leukaemia.