Translating advances in molecular oncology into improved care for patients with haematological malignancies

将分子肿瘤学的进步转化为改善血液恶性肿瘤患者的护理

• 批准号: nhmrc : 1079560
• 负责人: Prof Andrew Roberts
• 金额: $ 27.43万
• 依托单位: The Walter and Eliza Hall Institute of Medical Research
• 依托单位国家: 澳大利亚
• 项目类别: Practitioner Fellowships
• 财政年份: 2015
• 资助国家: 澳大利亚
• 起止时间: 2015-01-01 至 2019-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/translating-advances-molecular-haematological-malignancies/518674
• 关键词: Translating; advances; molecular; oncology; into

The purpose of my research is to develop and integrate into routine practice better treatment paradigms for patients with blood cancers – leukaemias, lymphomas, myeloma. My research seeks to (i) bring a new class of anti-cancer targeted therapy, inhibitors of Bcl-2, into routine care; (ii) discover the genetic changes that explain why slow growing lymphoid cancers change into rapidly fatal lymphomas; and (iii) integrate new molecular tests into the management of patients with acute leukaemia.

我研究的目的是为血癌患者（白血病、淋巴瘤、骨髓瘤）开发更好的治疗模式，并将其纳入常规实践。我的研究旨在（i）将一类新的抗癌靶向治疗，Bcl-2抑制剂，纳入常规护理;（ii）发现遗传变化，解释为什么缓慢生长的淋巴癌转变为快速致命的淋巴瘤;（iii）将新的分子检测纳入急性白血病患者的管理。