Australian Mouse Brain Mapping Consortium

我们建议建立澳大利亚小鼠脑测绘联盟，这是一个全国性的设施网络，使澳大利亚的研究人员能够更好地表征神经系统疾病（如阿尔茨海默病和中风）的小鼠模型。正如精确的地图是17世纪和18世纪地理发现之旅的关键一样，改进神经系统疾病小鼠模型大脑结构和功能变化的绘制方法，将是21世纪神经科学发现的关键。对于该联盟来说，制图工具将是磁共振成像（MRI）、显微镜和绘制大脑结构和功能的复杂计算方法。该联盟的参与者是国际公认的脑成像领域的领导者，他们分别位于莫纳什大学、霍华德弗洛里研究所、威尔士亲王医学研究所、磁共振中心和昆士兰大学的昆士兰脑研究所。

We propose to establish the Australian Mouse Brain Mapping Consortium which is a national network of facilities allowing Australian researchers to better characterise mouse models of neurological diseases such as Alzheimer's Disease and stroke. Just as accurate maps were key to the voyages of geographic discovery in the 17th and 18th century, improved methods of mapping structural and functional changes in the brain of mouse models of neurological disease will be key to discovery in the neurosciences in the 21st century . For the Consortium the cartographic tools will be magnetic resonance imaging (MRI), microscopy and sophisticated computational methods of mapping brain structure and function. Participants in the Consortium are internationally recognised leaders in brain imaging based at Monash University, the Howard Florey Institute, the Prince of Wales Medical Research Institute and the Centre for Magnetic Resonance and the Queensland Brain Institute, University of Queensland.