Australian Stroke Genetics Collaborative - Genome-wide association study in ischaemic stroke

大多数中风是由动脉粥样硬化血栓形成引起的，动脉血栓形成于脑血管中。许多基因与动脉粥样硬化血栓形成有关，但许多研究单独考察了环境风险因素对遗传的影响。我们将在环境风险因素的背景下，研究与动脉粥样硬化血栓形成相关的基因变异。通过确定遗传因素和环境因素在卒中中的贡献，我们将开发卒中风险评估工具。

The majority of stroke is caused by atherothrombosis, the formation of blood clots in brain blood vessels. Numerous genes are linked to atherothrombosis, but many studies examined genetic influences in isolation from environmental risk factors. We will examine the relevance of genetic variations linked to atherothrombosis, in the context of environmental risk factors. By determining the contribution of genetic and environmental factors in stroke, we will develop a stroke risk assessment tool.