Telemetry monitoring equipment to understand behavioral components of nutrition and metabolism

我的请求是购买新的数据科学国际（DSI）遥测生理监测设备适用于小动物（啮齿动物）。到目前为止，由于技术和成本的限制，我们在阿尔伯塔大学的营养小组还无法使用这种设备。该设备将使一个独特的和创新的复合数据采集，目前还没有在我们的研究环境中的任何地方。遥测设备是最先进的技术，可以在动物的正常行为环境中连续远程监测血压、体温、心脏电活动和身体活动。我们的研究项目目前将营养，肥胖和厌食症整合到饮食，体重和身体活动的单一神经化学模型中，这显然具有全球影响，包括心血管疾病（CVD）和其他体重相关疾病的风险。我们知道，体力活动或运动在这些疾病的能量消耗和能量平衡中起着重要作用。通过跨学科的合作，我们已经开发了肥胖和活动厌食症的小动物模型。膳食和营养补充剂对慢性疾病期间受影响的基本生理参数具有实质性影响，包括心血管疾病参数，如心脏功能（ECG）、呼吸和血压。此外，在食物限制期间通过轮运行破坏能量平衡需要在生理水平上获得更直接的证据，新DSI设备的影响将使人们对这一范式有创新的见解。因此，从这种新设备收集的数据将在营养，代谢，行为和社会学背景的广泛跨学科领域进行解释，这将允许更全面的综合HQP培训环境。这将是第一次，在A的U营养相关的计划将有机会获得这种类型的设备，特别是它将创新的跨学科行为营养方法，我们的研究计划。

My request is to purchase new Data Sciences International (DSI) telemetry physiologic monitoring equipment applicable for small animals (rodents). To date this equipment has been inaccessible to our Nutrition group at the University of Alberta due to limitations of technology and cost. The equipment will enable a unique and innovative composite of data acquisition that at present are not available anywhere within our research environment. The telemetric equipment is state-of the-art technology that can monitor blood pressure, temperature, heart electrical activity and physical activity, all remotely, on a continuous basis in the normal behavioral environment of the animal. Our research programs currently integrate nutrition, obesity and anorexia within a single neurochemical model of eating, body weight and physical activity, which clearly has global implications including risks for cardiovascular disease (CVD) and other weight-related disorders. We know that physical activity or exercise plays an important role in energy expenditure and energy balance in these disorders. Through cross-discipline collaborations at the U of A, we have developed small animal models for both obesity and activity anorexia. Dietary and nutritional supplementation has a substantive impact on basic physiological parameters affected during chronic disease including CVD parameters such as cardiac function (ECG), respiration and blood pressure. Moreover, the disruption of energy balance by wheel running during food-restriction requires more direct evidence at the physiological level and the impact of the new DSI equipment will enable innovative insights into this paradigm. Consequently, data collected from this new equipment will be interpreted across broad trans-disciplinary fields of nutrition, metabolism, behavioral and sociological contexts, which will allow a more comprehensive integrated HQP training environment. It will be the first time that nutritional-related programs at the U of A will have access to this type of equipment, in particular it will innovate the trans-disciplinary behavioral-nutritional approach to our research program.