Building an intestine: manipulating regeneration of the epithelium

疾病、感染和病理是婴幼儿和成人肠道衬里的常见临床问题。患有这些疾病的人可能会出现营养问题，严重的情况会导致死亡。肠壁是由一小群干细胞产生的。在这项研究中，我们使用了标记干细胞的小鼠模型，并将检查哪些因素调节肠道中的干细胞，目的是促进肠道组织的再生。

Diseases, infections and pathologies are common clinical problems of the intestinal lining in both infants and adults. Individuals with these conditions can experience nutritional problems and severe cases result in death. The intestinal lining is generated from a small population of stem cells. In this study we use of a mouse model where the stem cells are marked and will examine what factors regulate stem cells in the intestine with the aim of facilitating intestinal tissue regeneration.