CCR9 expressing T helper cells in immunity and autoimmunity
CCR9 expressing T helper cells in immunity and autoimmunity
批准号:
nhmrc : 1066243
负责人:
A/Pr Cecile King
金额:
$48.65万
依托单位国家:
澳大利亚
项目类别:
Project Grants
财政年份:
2014
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2014-01-01 至 2016-12-31
中文摘要
我们已经在自身免疫性病变中鉴定了一种独特的免疫细胞亚群,称为Tccr9细胞。你在肠道中发现这些细胞,但当身体进入疾病模式时,Tccr9细胞会传播到消化系统的附属器官。了解肠道Tccr9细胞与导致慢性炎症和自身免疫的Tccr9细胞之间的关系是这项研究提案的重点。
英文摘要
We have identified a unique subset of immune cells in autoimmune lesions named Tccr9 cells. You find these cells in the gut, but when the body shifts into disease mode, Tccr9 cells disseminate to the accessory organs of the digestive system. Understanding the relationship between gut Tccr9 cells and the Tccr9 cells that contribute to chronic inflammation and autoimmunity is the focus of this research proposal.
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会议论文
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依托单位:
The role of Interleukin-21 in the pathogenesis of autoimmune diabetes
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负责人:A/Pr Cecile King
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依托单位:
海外基金