Cell division mechanisms and anti-cancer drugs

有丝分裂是细胞分裂周期的最后阶段，产生两个子细胞。调节这一过程的蛋白质不正确的定位和修饰会导致细胞分裂错误，可能导致癌症。这个项目将描述关键的有丝分裂蛋白如何协同作用来完成这一过程。这项研究将增加我们对细胞分裂错误的理解，这些错误有助于癌症的发展，最终确定癌症治疗的新靶点。

Mitosis is the final stage of the cell division cycle that produces two daughter cells. Incorrect localisation and modification of proteins that regulate this process cause cell division errors potentially leading to cancer. This project will characterise how key mitotic proteins co-operatively function to complete this process. This research will increase our understanding of the cell division errors that contribute to cancer development, ultimately identifying new targets for cancer therapy.