Characterisation of neural stem cells in the ageing mammalian brain

由于他们相对较新的发现，人们对大脑中的干细胞如何受到年龄的影响知之甚少。这项工作最初将侧重于了解年龄如何影响大脑中发现的干细胞数量，以及它们的正常功能和再生能力如何随着年龄的增长而受到损害。这项研究的第二阶段将研究我们如何通过环境操纵来减缓甚至逆转干细胞上这些与年龄相关的变化。

Due to their relatively recent discovery, little is known about how stem cells in the brain are affected by age. This work will initially focus on understanding how age affects the number of stem cells found in the brain, and how their normal function and regenerative capacity are compromised with increasing age. The second phase of this study will examine how we can slow or even reverse these age-related changes on stem cells by environmental manipulation.