Characterization of Sex-Specific Differences in Cardiovascular Adaptation in the First Three Years of Life

明显早产的男婴死亡率是女婴的两倍。其原因尚不清楚。这项研究将确定男性和女性早产儿的心血管差异，并将检查他们在头5天内的适应情况。确定导致两性死亡率差异的机制也将显示出出生前后的变化如何影响血压系统的终身功能，这是一生中中风的主要风险。

Male babies born significantly premature are up to twice likely to die than females. The reasons for this are unknown. This study will determine the cardiovascular differences in male and female babies born preterm and will examine how they adapt over the first 5 days. Defining the mechanisms that contribute to the difference in mortality between the sexes will also show how changes starting around birth affect the way the blood pressure system functions for life, a major lifetime stroke risk.