Regulation of energy homeostasis by Palmitoyl CoA

身体的正常功能有赖于维持能量平衡，使需求和供应相匹配。人体通过监测代谢物浓度来感知自身的能量状态。我发现了一种代谢物，它控制着体内能量、动态平衡和食欲的多种关键酶，可能会为解决肥胖相关疾病提供新的方法。我在许多蛋白质中发现了代谢物结合口袋，它可能代表了一个重要的新调控网络。

The body’s normal function depends upon maintaining energy balance matching demand and supply. The body senses its energy status by monitoring metabolite concentrations. I have discovered a metabolite that controls multiple enzymes critical for energy homeostasis and appetite in the body that may provide new approaches to tackle obesity related disease. I have found the metabolite-binding pocket in many proteins and it may represent a major new regulatory network.