The role of glycaemic variability in influenza virus pathogenesis and immunity

糖尿病患者有感染严重流感的风险。然而，驱动这种易感性的机制尚不完全清楚。该项目将调查糖尿病患者的血糖水平变化是否会增加流感的严重程度，并通过引起氧化应激损害免疫反应。在此过程中，该项目旨在确定减少氧化应激是否会降低糖尿病患者患流感的严重程度。

People with diabetes are at risk of severe flu infections. However, the mechanisms that drive this susceptibility are incompletely understood. This project will investigate whether variable blood sugar levels in patients with diabetes increase the severity of the flu and impair the immune response by causing oxidative stress. In doing so, this project aims to identify if reducing oxidative stress will reduce the severity of the flu in patients with diabetes.