Role of the LIM-only protein LMO4 in lung development and lung cancer

肺癌是澳大利亚癌症患者死亡的主要原因。虽然治疗方法在过去10年中有所改善，但人们仍热切期待新的治疗策略。在癌症中经常观察到驱动正常组织发育的分子失调。我们的目的是确定肺发育和损伤后肺修复的关键调节因子。我们的目标是评估这些分子在肺癌的发生和发展中的作用，以确定新的治疗靶点。

Lung cancer is the leading cause of death in cancer patients in Australia. Although treatments have improved in the past 10 years, new therapeutic strategies are eagerly awaited. Deregulation of molecules driving development of normal tissue is often observed in cancer. Our aim is to identify key regulators of lung development and lung repair after injury. We aim to evaluate the role of these molecules in the initiation and progression of lung cancer to identify new targets for therapies.