The role of a novel cytokine of the innate immune response in viral infection

性传播感染是一个严重的全球健康和社会经济问题，每年新增病例超过10亿例。我提出了一种世界上第一次描述一种新的蛋白质，它对女性生殖道的单纯疱疹病毒(HSV)感染具有保护作用。这种独特的蛋白质被称为干扰素epsilon，是在我们实验室发现的。该项目将促进对HSV-2感染有益的新治疗方法的开发。

Sexually transmitted infections represent a critical global health and socioeconomic problem with over 1 billion new cases per annum. I propose a world-first description of a new protein that has a protective role against herpes simplex virus (HSV) infection of female reproductive tract. This unique protein, called interferon epsilon, was discovered in our laboratory. This project will facilitate development of new therapeutic approaches of benefit in HSV-2 infection.