The role of Rab GTPases and Rab GTPase activating proteins in Insulin Action

2型糖尿病是世界上增长最快的疾病之一。虽然生活方式因素导致了这一点，但我们必须了解胰岛素在正常情况下是如何发挥作用的，以帮助抗击这种疾病。我们的目标是为胰岛素在糖尿病中被破坏的主要代谢作用之一--葡萄糖向肌肉和脂肪细胞的运输提供分子蓝图。在过去的几年里，我们已经开始填补这个谜团中缺失的部分。

Type 2 diabetes is one of the most rapidly growing diseases in the world. While lifestyle factors have contributed to this we must understand how insulin works under normal circumstances to aid in the fight against this disease. Our goal is to provide the molecular blueprint for one of insulin's major metabolic actions that is disrupted in diabetes - glucose transport into muscle and fat cells. Over the past few years we have begun to fill in the missing pieces to this puzzle.