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The Role of Tissue Factor Pathway Inhibitor (TFPI) in the Pathogenesis of Lymphatic Malformations

The Role of Tissue Factor Pathway Inhibitor (TFPI) in the Pathogenesis of Lymphatic Malformations
组织因子途径抑制剂 (TFPI) 在淋巴管畸形发病机制中的作用
批准号:
nhmrc : 1039096
负责人:
Dr Jenny Than
金额:
$5.81万
依托单位:
依托单位国家:
澳大利亚
项目类别:
NHMRC Postgraduate Scholarships
财政年份:
2012
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2012-01-01 至 2013-12-31

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中文摘要
翻译
淋巴管畸形或囊性水瘤是一种叫做“淋巴管”的异常血管的生长。它们在出生时就存在,通常会影响头部和颈部,并可能由于体型增长和频繁感染而导致终生问题。手术治疗并不能提供治愈的方法,而且这些问题往往会持续终生。血液凝块在这些生长过程中不断形成和分解的发现,可能为缓解症状和了解这种情况的原因提供线索。
英文摘要
Lymphatic malformations or cystic hygomas are growths of abnormal blood vessels called 'lymphatic vessels'. They are present at birth, commonly affect the head and neck, and can cause lifelong problems due to growth in size and frequent infections. Surgical treatment does not offer a cure, and problems often persist lifelong. The finding that blood clots are continuously forming and breaking down in these growths may provide a clue to relieving symptoms and understanding the cause of this condition.
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