Scarlet fever pandemic and reversing antibiotic resistance
Scarlet fever pandemic and reversing antibiotic resistance
批准号:
nhmrc : 1194130
负责人:
金额:
$341.42万
依托单位国家:
澳大利亚
项目类别:
Investigator Grants
财政年份:
2021
资助国家:
澳大利亚
项目状态:
未结题
起止时间:
2021-01-01 至 2025-12-31
中文摘要
(1)猩红热是一种由A组链球菌(GAS)突然卷土重来的疾病(自2011年以来已有60万例)。为了控制疫情,我的团队将开发一种猩红热疫苗。(2)我的团队发现了一类安全的化合物,可以打破抗生素耐药性,恢复抗生素效力。我们现在将把这一令人兴奋和无与伦比的发现转化为治疗抗生素耐药超级细菌的临床。
英文摘要
(1) Scarlet fever is a disease caused by the bacterial pathogen group A Streptococcus (GAS) that has abruptly re-emerged (>600,000 cases since 2011). To contain this outbreak, my team will develop a scarlet fever vaccine. (2) My team has discovered a class of safe compounds that break antibiotic resistance, restoring antibiotic efficacy. We will now translate this exciting and unparalleled discovery into the clinic for the treatment of antibiotic resistant superbugs.
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