Sequencing Periodontal Bacteria To Determine The Relationship Between Periodontits, Renal And Vascular Function Among Indigenous Australian Adults With Chronic Kidney Disease
Sequencing Periodontal Bacteria To Determine The Relationship Between Periodontits, Renal And Vascular Function Among Indigenous Australian Adults With Chronic Kidney Disease
批准号:
nhmrc : 1113098
负责人:
金额:
$22.61万
依托单位国家:
澳大利亚
项目类别:
Early Career Fellowships
财政年份:
2016
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2016-01-01 至 2019-12-31
中文摘要
近20%的澳大利亚土著成年人表现出肾脏疾病的迹象。本研究将调查患有慢性肾病的澳大利亚土著参与者的牙龈下细菌与肾脏和动脉功能之间的关系。采用随机对照试验设计,该研究将调查牙周炎常规治疗后龈下细菌和浓度的变化是否与肾脏和血管功能的改善相一致。
英文摘要
Almost 20% of Indigenous Australian adults exhibit signs of kidney disease. This study will investigate the relationship between sub-gingival (below the gum) bacteria and both kidney and artery function among Indigenous Australian participants with chronic kidney disease. Using an RCT design, the proposed study will investigate whether changes in sub-gingival bacteria and concentration following conventional treatment of periodontitis align with improvements in renal and vascular function.
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