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Environmental parameters, physiological factors and the chemistry of decomposition

Environmental parameters, physiological factors and the chemistry of decomposition
环境参数、生理因素和分解化学
批准号:
327394-2006
负责人:
Forbes, Shari
金额:
$2.33万
依托单位国家:
加拿大
项目类别:
Discovery Grants Program - Individual
财政年份:
2008
资助国家:
加拿大
项目状态:
已结题
起止时间:
2008-01-01 至 2009-12-31

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中文摘要
翻译
分解化学的研究是一个相对较新的研究领域,它研究在分解过程中发生在体内的化学分解过程。这一领域的研究需要跨学科的方法,重点是分析化学,生物化学和环境科学。通过调查降解过程中发生的分解阶段和它们的变化,由于生理因素和环境参数,本研究的目的是确定特征的生化签名使用色谱技术和多元统计。这项研究在食品科学行业中有一个小的应用,因为许多发酵或分解的食品都有受到有毒污染的风险,这在社会上造成了严重的健康问题。更好地了解软组织的化学降解过程可以为发酵肉类和其他食品提供有用的质量标志。这项研究的主要应用是在法医学领域。在刑事调查中出现的最重要的决定因素之一是准确确定腐烂遗骸死亡后的时间。目前估计这一间隔的方法无法同时考虑生理和环境的影响。因此,提供一种既考虑生理因素又考虑环境因素的估计死亡时间的方法,将大大提高估计的准确性,这对民事、刑事和法医案件的公正结果至关重要。
英文摘要
The study of decomposition chemistry is a relatively new area of research which investigates the chemical breakdown processes that occur in the body as decomposition proceeds. Research in this area requires an interdisciplinary approach focusing on analytical chemistry, biochemistry, and environmental science. By investigating the degradation processes which occur during the decomposition phase and their variation due to physiological factors and environmental parameters, the research aims to identify characteristic biochemical signatures using chromatographic techniques and multivariate statistics. The research has a minor application in the food science industry as many fermented or decomposed foods are subject to the risk of toxic contamination which presents serious health issues in society. A better understanding of the chemical degradation process of soft tissue can provide useful quality markers of fermented meats and other food products. The major application of this research is in the field of forensic science. One of the most important determinants to arise in a criminal investigation is the accurate determination of time since death of decomposed remains. Current methods for estimating this interval are unable to take into consideration both the physiological and environmental influence. Hence the provision of a method for estimating time since death which considers both physiological and environmental factors would greatly enhance the accuracy of estimations which is critical to the impartial outcome of civil, criminal and forensic cases.
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Discovery of biomarker signatures to accurately estimate time since death
Canada 150 Research Chair in Forensic Thanatology
Characterising chemical markers of decomposition to advance death investigations
  • 批准号:
    RGPIN-2019-06098
  • 项目类别:
    Discovery Grants Program - Individual
  • 资助金额:
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  • 财政年份:
    2022
  • 负责人:
    Forbes, Shari
  • 依托单位:
Characterising chemical markers of decomposition to advance death investigations
  • 批准号:
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  • 项目类别:
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  • 资助金额:
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  • 财政年份:
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  • 负责人:
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