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Effects of cortical arousal changes due to sleepiness, alcohol & coffeine on EEG/ERP measures of performance and brain function

Effects of cortical arousal changes due to sleepiness, alcohol & coffeine on EEG/ERP measures of performance and brain function
困倦、酒精对皮质唤醒变化的影响
批准号:
341576-2008
负责人:
Murphy, Timothy
金额:
$1.09万
依托单位:
依托单位国家:
加拿大
项目类别:
Discovery Grants Program - Individual
财政年份:
2008
资助国家:
加拿大
项目状态:
已结题
起止时间:
2008-01-01 至 2009-12-31

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中文摘要
翻译
这项研究将考察几种挑战对日常功能的影响,如嗜睡、轻度醉酒和对风险的反应。行为表现和大脑活动将在睡眠不足、饮酒和赌博(危险)情况下进行评估。此外,还将研究咖啡因,这是一种逆转嗜睡和醉酒影响的常见对策。我将在摄入足够酒精之前和之后对个人进行测试,以将他们的血液酒精浓度提高到大约0.04(许多省份开车的法定上限的一半)和/或大约20个小时的清醒后。我将评估他们在各种任务中的表现,同时收集脑电数据(大脑皮层活动)。我还将测试一种常见对策咖啡因的有效性(在行为和脑电方面)。在我的实验中,这些人在接受重新测试以确定他们的表现是否有所改善,或者他们的大脑活动是否恢复到正常水平之前,将获得相当于2杯咖啡的量。
英文摘要
This research will examine the effects of several challenges to everyday functioning such as sleepiness, mild intoxication and reaction to risk. Behavioural performance and brain activity will be assessed under conditions of sleep deprivation, alcohol consumption and during a gambling (risky) situtation. In addition, caffeine, a common countermeasure taken to reverse the effects of sleepiness and intoxication will be examined. I will test individuals before and after ingesting enough alcohol to raise their blood alcohol to approximately .04 (half the legal limit to drive in many provinces) and/or after approximately 20 hours of wakefulness. I will assess their performance on a variety of tasks while also collecting EEG data (brain electrocortical activity). I will also test the effectiveness (behaviourally and in terms of EEG) of a common countermeasure, caffeine. The individuals in my experiments will receive the equivalent of approximately 2 cups of coffee before being retested to determine if their performance improves, or their brain activity returns to normal levels.
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会议论文
Tools for assessing shared sensory experience in interacting mice.
  • 批准号:
    RGPIN-2022-03723
  • 项目类别:
    Discovery Grants Program - Individual
  • 资助金额:
    $4.01万
  • 财政年份:
    2022
  • 负责人:
    Murphy, Timothy
  • 依托单位:
Effects of cortical arousal changes due to sleepiness, alcohol & coffeine on EEG/ERP measures of performance and brain function
  • 批准号:
    341576-2008
  • 项目类别:
    Discovery Grants Program - Individual
  • 资助金额:
    $1.09万
  • 财政年份:
    2009
  • 负责人:
    Murphy, Timothy
  • 依托单位:
国内基金
海外基金
Cortical control of internal state in the insular cortex-claustrum region
Cortical Hem与FoxG1相互作用调控齿状回发育的分子机制研究
  • 批准号:
    31171040
  • 项目类别:
    面上项目
  • 资助金额:
    58.0万元
  • 批准年份:
    2011
  • 负责人:
    赵春杰
  • 依托单位:
损伤和修复过程中皮层神经元钙稳态调控机制研究
  • 批准号:
    30670500
  • 项目类别:
    面上项目
  • 资助金额:
    28.0万元
  • 批准年份:
    2006
  • 负责人:
    柴真
  • 依托单位:
去除corticl hem 对大脑皮层和海马发育的影响
  • 批准号:
    30440090
  • 项目类别:
    专项基金项目
  • 资助金额:
    8.0万元
  • 批准年份:
    2004
  • 负责人:
    赵春杰
  • 依托单位: