SNAC2: A randomised trial of extending sentinel node based management to women with larger or multifocal breast cancers

SNAC2扩展了SNAC1开始的工作，SNAC1在4年内招募了1088名妇女。SNAC1将决定前哨淋巴结活检引起的上肢问题是否少于腋窝清除。SNAC2的目的是确定前哨淋巴结活检的局部复发风险和长期安全性，特别是对于较大或多发性肿瘤的女性。需要SNAC2来确定小手术的治愈率是否和腋窝清除率一样好。如果是这样，那么它将成为标准做法。

SNAC2 extends the work begun in SNAC1, which recruited 1,088 women over 4 years. SNAC1 will determine if sentinel node biopsy causes less arm problems than axillary clearance. The goal of SNAC2 is to establish the risk of local recurrence and long term safety of sentinel node biopsy, especially for women with larger or multiple tumours. SNAC2 is needed to determine whether the smaller operation gives cure rates as good as axillary clearance. If it does, then it will become standard practice.