Structural studies of the GABA receptor

这项建议涉及一种名为GABA受体的蛋白质的生化研究，它是各种抗焦虑药物(抗焦虑药物)、抗惊厥药物、镇静剂、镇静剂、抗癫痫药物、酒精和麻醉剂的已知靶标。这项工作有望确定该蛋白质的三维形状，为该蛋白质的工作原理提供必要的信息，并为设计和开发控制癫痫、作为全身麻醉剂、缓解焦虑和诱导睡眠的新药奠定基础。

This proposal concerns the biochemical investigation of a protein called GABA receptor which is a known target for various anti-anxiety drugs (anxiolytics), anti-convulsants, sedatives, depressants, anti-epilespy drugs, alcohol and anaesthetics. This work is expected to lead to the determination of the three-dimensional shape of the protein which will provide essential information about how the protein works and lay the foundation for the design and development of new drugs to control epilepsy, act as general anaesthetics, relieve anxiety and induce sleep.