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Spectroscopy and biosensors for turbid media

Spectroscopy and biosensors for turbid media
浑浊介质的光谱学和生物传感器
批准号:
155504-2008
负责人:
Burns, David
金额:
$3.21万
依托单位:
依托单位国家:
加拿大
项目类别:
Discovery Grants Program - Individual
财政年份:
2009
资助国家:
加拿大
项目状态:
已结题
起止时间:
2009-01-01 至 2010-12-31

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中文摘要
翻译
这项工作的目标是在散射介质中开发高浓度和低浓度成分的定量、深度分辨测量。可变散射限制了细胞悬液和组织测量中分析物的定量。对于高浓度组分,我们建议将光学图案化照明与近红外光谱和化学计量学相结合,以提供深度分辨定量。我们将使用分散的超声活性微型传感器来扩展对低浓度分析物的检测灵敏度,这种传感器可以在分析物结合时改变光学和超声波性质。将采取的具体目标分为两个平行的努力:
英文摘要
The goal of this work is to develop quantitative, depth-resolved measurements in scattering media for both high and low concentration consituents. Variable scattering limits quantification of analytes in cell suspensions and tissue measurements. For high concentration components we propose to combine optical patterned illumination with near-infrared spectroscopy and chemometrics, to provide depth-resolved quantification. We will extend the sensitivity of detection for low concentration analytes using dispersed ultrasonically active micro-sensors, which change optical and ultrasonic properties upon analyte binding. The specific objectives to be undertaken are divided into two parallel efforts:
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Virtual Workshop - Advanced Manufacturing
  • 批准号:
    537101-2018
  • 项目类别:
    Connect Grants Level 2
  • 资助金额:
    $0.46万
  • 财政年份:
    2018
  • 负责人:
    Burns, David
  • 依托单位:
Determination of cleaning efficiency of used cleaning and degreasing solutions by optical and acoustic spectroscopy
  • 批准号:
    503224-2016
  • 项目类别:
    Engage Grants Program
  • 资助金额:
    $1.82万
  • 财政年份:
    2016
  • 负责人:
    Burns, David
  • 依托单位:
Design, implementation, and evaluation of a novel paradigm for surgical navigation in orthopedics
  • 批准号:
    482061-2015
  • 项目类别:
    Alexander Graham Bell Canada Graduate Scholarships - Master's
  • 资助金额:
    $1.27万
  • 财政年份:
    2015
  • 负责人:
    Burns, David
  • 依托单位:
Canadian First Research Excellence Fund: Transitioning our bioresource economy - Leadership and innovation in bioproducts (Full proposal planning session)
  • 批准号:
    491876-2015
  • 项目类别:
    Regional Office Discretionary Funds
  • 资助金额:
    $0.11万
  • 财政年份:
    2015
  • 负责人:
    Burns, David
  • 依托单位:
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